Contact

  • Rigshospitalet, Dept. 7812,
    The Copenhagen University Hospital, DK
  • Postal address:
    Blegdamsvej 9, DK-2100 Copenhagen Ø
  • Visiting address:
    Tagensvej 22, DK-2200 Copenhagen N
  • Tel.: +45 3545 7171
    Fax: +45 3545 7101
  • News and announcements

    • By the 1st of March 2017, the CTU has reached 677 publications, over 2900 yearly references to its publications, and a h-index of 64 (please see About the CTU, History of the CTU).
    • Full publication list of CTU 1995-2016 View.
    • Cochrane review from 2014 by Epstein, Patsopoulos, and Weiser on immediate-release methylphenidate (Ritalin®) for adults with attention deficit hyperactivity disorder (ADHD) withdrawn after critique from The Copenhagen Trial Unit as well as from others. The decision to withdraw the review was taken after prolonged criticism raised against serious flaws in the included trials; serious defects in assessments, analyses, and drawn conclusions; lack of authors’ responses to raised critique; and authors’ conflicts of interests. See the full review and the raised critique as well as the withdrawal statements. View, View.
    • Wetterslev J, et al. Trial Sequential Analysis in systematic reviews with meta-analysis. BMC Medical Research Methodology 2017;17(39):1-18. View.
    • Jakobsen JC, et al. Selective serotonin reuptake inhibitors versus placebo in patients with major depressive disorder. A systematic review with meta-analysis and Trial Sequential Analysis. BMC Psychiatry 2017;17:58. View.
    • Imberger G, et al. False-positive findings in Cochrane meta-analyses with and without application of trial sequential analysis: an empirical review. BMJ Open 2016;6:e011890 doi:10.1136/bmjopen-2016-011890. View.
    • The Nordic Trial Alliance Working Group 6. Report on transparency and registration in clinical research in the Nordic countries. View.
    • Garattini S, et al. Evidence-based clinical practice: Overview of threats to the validity of evidence and how to minimise them. Eur J Intern Med 2016;32:13-21. View.
    • Storebø OJ, et al. Methylphenidate for attention-deficit/hyperactivity disorder in children and adolescents. JAMA Clinical Evidence Synopsis 2016;315(18):2009-2010. View.
    • Jakobsen JC, et al. Viewpoint: taking into account risks of random errors when analysing multiple outcomes in systematic reviews. Cochrane Database Syst Rev 2016;3:ED000111. View.
    • Nørskov AK, et al. Prediction of difficult mask ventilation using a systematic assessment of risk factors vs. existing practice – a cluster randomised clinical trial in 94,006 patients. Anaesthesia 2016;72:doi:10.1111/anae.13701 View.
    • Karam O, et al. The effect of inhaled nitric oxide in acute respiratory distress syndrome in children and adults: a Cochrane systematic review with trial sequential analysis. Anaesthesia 2017;72:106-117. View.
    • Albert N, et al. Five years of specialised early intervention versus two years of specialised early intervention followed by three years of standard treatment for patients with a first episode psychosis: randomised, superiority, parallel group trial in Denmark (OPUS II). BMJ 2017;356:i6681. View.

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    The Copenhagen Trial Unit

    Welcome to the Copenhagen Trial Unit – the CTU.

    The CTU is a clinical intervention research unit conducting clinical research within all specialities.

    We offer flexible collaboration and consulting at all stages of clinical research.

    We provide expertise and infrastructure in planning, conduct, analysis, and interpretation of randomised clinical trials, including development of trial methodology and education.

    The CTU has been involved in the conduct of more than 400 protocols for systematic reviews, which has materialised in the publication of more than 250 systematic reviews published within and outside The Cochrane Collaboration. The CTU has developed methodology and software for conducting trial sequential analyses (TSA).

    We provide advice, support, and full collaboration during the protocol and systematic review development. We offer expertise in search strategy design, conduct literature searches for systematic reviews, and offer help with or conduct of meta-analyses.

    The CTU has been involved in the conduct of more than 125 randomised clinical trials in which more than 116,000 participants were randomised.

    The CTU hosts the Editorial Team Office of the Cochrane Hepato-Biliary Group (CHBG)) - one of the 53 global Collaborative Review Groups within The Cochrane Collaboration - as well as the Danish Clinical Research Infrastructures Network (DCRIN), the Danish coordinating hub of the Nordic Trial Alliance (NTA), and the Danish coordinating hub of the European Clinical Research Infrastructures Network (ECRIN).

     

     

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