• Rigshospitalet, Dept. 7812,
    The Copenhagen University Hospital, DK
  • Postal address:
    Blegdamsvej 9, DK-2100 Copenhagen Ø
  • Visiting address:
    Tagensvej 22, DK-2200 Copenhagen N
  • Tel.: +45 3545 7171
    Fax: +45 3545 7101
  • News and announcements

    • Full publication list of CTU 1995-2015 View.
    • Cochrane review from 2014 by Epstein, Patsopoulos, and Weiser on immediate-release methylphenidate (Ritalin®) for adults with attention deficit hyperactivity disorder (ADHD) withdrawn after critique from The Copenhagen Trial Unit as well as from others. The decision to withdraw the review was taken after prolonged criticism raised against serious flaws in the included trials; serious defects in assessments, analyses, and drawn conclusions; lack of authors’ responses to raised critique; and authors’ conflicts of interests. See the full review and the raised critique as well as the withdrawal statements. View, View.
    • Fonnes S, et al. Perioperative hyperoxia - Long-term impact on cardiovascular complications after abdominal surgery, a post hoc analysis of the PROXI trial. 2016. International Journal of Cardiology. 215(2016):238-243. View.
    • Hansen MS, et al. Post-operative serious adverse events in a mixed surgical population - a retrospective register study. 2016 Jul 14. Acta Anaesthesiologica Scandinavica. (Epub ahead of print). View.
    • Imberger G, et al. False-positive findings in Cochrane meta-analyses with and without application of trial sequential analysis: an empirical review. 2016 August 12. BMJ Open. 6:e011890 doi:10.1136/bmjopen-2016-011890. View.
    • The Nordic Trial Alliance Working Group 6. Report on transparency and registration in clinical research in the Nordic countries. View.
    • Garatini S, et al. Evidence-based clinical practice: Overview of threats to the validity of evidence and how to minimise them. 2016 May 5. Eur J Intern Med. View.
    • Storebø OJ, et al. Methylphenidate for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents. 2016 May 10. JAMA Clinical Evidence Synopsis. 315(18): 2009-2010. View.
    • Jakobsen JC, et al. Viewpoint: taking into account risks of random errors when analysing multiple outcomes in systematic reviews. 2016 Mar 18. Cochrane Database Syst Rev. 3: ED000111. View.

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    The Copenhagen Trial Unit

    Welcome to the Copenhagen Trial Unit – the CTU.

    The CTU is a clinical intervention research unit conducting clinical research within all specialities.

    We offer flexible collaboration and consulting at all stages of clinical research.

    We provide expertise and infrastructure in planning, conduct, analysis, and interpretation of randomised clinical trials, including development of trial methodology and education.

    The CTU has been involved in the conduct of more than 400 protocols for systematic reviews, which has materialised in the publication of more than 250 systematic reviews published within and outside The Cochrane Collaboration. The CTU has developed methodology and software for conducting trial sequential analyses (TSA).

    We provide advice, support, and full collaboration during the protocol and systematic review development. We offer expertise in search strategy design, conduct literature searches for systematic reviews, and offer help with or conduct of meta-analyses.

    The CTU has been involved in the conduct of more than 125 randomised clinical trials in which more than 116,000 participants were randomised.

    The CTU hosts the Editorial Team Office of the Cochrane Hepato-Biliary Group (CHBG)) - one of the 53 global Collaborative Review Groups within The Cochrane Collaboration - as well as the Danish Clinical Research Infrastructures Network (DCRIN), the Danish coordinating hub of the Nordic Trial Alliance (NTA), and the Danish coordinating hub of the European Clinical Research Infrastructures Network (ECRIN).



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